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Research published to support vaccine benefit in household transmission

The Health Security Agency (UKHSA) has published a compilation of research studies supporting the benefit of COVID-19 vaccination for self, and for others living in the same household.

The reports cover the impact of the COVID-19 vaccines on:

  • symptomatic disease
  • hospitalisation
  • death
  • infection (symptomatic or asymptomatic).

Published research includes the following:

  • Impact of vaccination on household transmission of SARS-COV-2 in England. This finds that the likelihood of household transmission was approximately 40 to 50 per cent lower in households of people who had been vaccinated 21 days or more before testing positive than in households of unvaccinated index patients
  • The VIVALDI study found evidence that COVID-19 vaccines were associated with a substantially reduced risk of infection in care home residents
  • The SIREN study which shows a promising impact on infection in healthcare workers aged under 65.  

There is also information on the effectiveness of different vaccine dosing schedules.


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